Gene name:
Anpep (Lap-1;Lap1) ;
Protein name:
Aminopeptidase N (AP-N;mAPN) ;
Alternative:
Aminopeptidase M (AP-M) ;Alanyl aminopeptidase ;Microsomal aminopeptidase ;Membrane protein p161 ;
CD:
CD13 ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Broad specificity aminopeptidase. Plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. May be involved in the metabolism of regulatory peptides of diverse cell types. May have a role in angiogenesis (By similarity). Found to cleave antigen peptides bound to major histocompatibility complex class II molecules of presenting cells.
Subcellular Location:
Membrane
Single-pass type II membrane protein
Protein Attributes:
50:
MAKGFYISKT | LGILGILLGV | AAVCTIIALS | VVYAQEKNRN | AENSATAPTL |
100:
PGSTSATTAT | TTPAVDESKP | WNQYRLPKTL | IPDSYRVILR | PYLTPNNQGL |
150:
YIFQGNSTVR | FTCNQTTDVI | IIHSKKLNYT | LKGNHRVVLR | TLDGTPAPNI |
200:
DKTELVERTE | YLVVHLQGSL | VEGRQYEMDS | QFQGELADDL | AGFYRSEYME |
250:
GDVKKVVATT | QMQAADARKS | FPCFDEPAMK | AMFNITLIYP | NNLIALSNML |
300:
PKESKPYPED | PSCTMTEFHS | TPKMSTYLLA | YIVSEFKNIS | SVSANGVQIG |
350:
IWARPSAIDE | GQGDYALNVT | GPILNFFAQH | YNTSYPLPKS | DQIALPDFNA |
400:
GAMENWGLVT | YRESSLVFDS | QSSSISNKER | VVTVIAHELA | HQWFGNLVTV |
450:
AWWNDLWLNE | GFASYVEYLG | ADYAEPTWNL | KDLMVLNDVY | RVMAVDALAS |
500:
SHPLSSPADE | IKTPDQIMEL | FDSITYSKGA | SVIRMLSSFL | TEDLFKKGLS |
550:
SYLHTYQYSN | TVYLDLWEHL | QKAVNQQTAV | QPPATVRTIM | DRWILQMGFP |
600:
VITVNTNTGE | ISQKHFLLDS | KSNVTRPSEF | NYIWIAPIPF | LKSGQEDHYW |
650:
LDVEKNQSAK | FQTSSNEWIL | LNINVTGYYL | VNYDENNWKK | LQNQLQTDLS |
700:
VIPVINRAQI | IHDSFNLASA | KMIPITLALD | NTLFLVKEAE | YMPWQAALSS |
750:
LNYFTLMFDR | SEVYGPMKRY | LKKQVTPLFF | YFQNRTNNWV | NRPPTLMEQY |
800:
NEINAISTAC | SSGLKECRDL | VVELYSQWMK | NPNNNTIHPN | LRSTVYCNAI |
850:
AFGGEEEWNF | AWEQFRNATL | VNEADKLRSA | LACSKDVWIL | NRYLSYTLNP |
900:
DYIRKQDTTS | TIISIASNVA | GHPLVWDFVR | SNWKKLFENY | GGGSFSFANL |
950:
IQGVTRRFSS | EFELQQLEQF | KADNSATGFG | TGTRALEQAL | EKTRANIDWV |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Pig
Chicken
Rat
Rabbit
Dog
Bovine
Polyclonal Antibody for Mouse AP-N
Polyclonal Antibody for Mouse AP-N
Polyclonal Antibody for Mouse AP-N
Polyclonal Antibody for Mouse AP-N
Polyclonal Antibody for Mouse AP-N
Polyclonal Antibody for Mouse AP-N
Polyclonal Antibody for Mouse AP-N
Polyclonal Antibody for Mouse AP-N
Monoclonal Antibody for Mouse AP-N
Monoclonal Antibody for Mouse AP-N
Monoclonal Antibody for Mouse AP-N
Monoclonal Antibody for Mouse AP-N
Monoclonal Antibody for Mouse AP-N
Monoclonal Antibody for Mouse AP-N
Monoclonal Antibody for Mouse AP-N
Monoclonal Antibody for Mouse AP-N
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 538-564; 886-908; 922-942 AND 961-965;TISSUE SPECIFICITY
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Czech II .
strain :
FVB/N .
tissue :
Mammary tumor .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;ENZYMATIC CLEAVAGE OF ANTIGEN PEPTIDES BOUND TO CLASS II MHC
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ENZYMATIC CLEAVAGE OF ANTIGEN PEPTIDES BOUND TO CLASS II MHC
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-852;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Mast cell .
6.
"The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation."
Gundry R.L.
,
Raginski K.
,
Tarasova Y.
,
Tchernyshyov I.
,
Bausch-Fluck D.
,
Elliott S.T.
,
Boheler K.R.
,
Van Eyk J.E.
,
Wollscheid B.
Mol. Cell. Proteomics8:2555-2569(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-106; ASN-128; ASN-606; ASN-666; ASN-783; ASN-784; ASN-785; ASN-790 AND ASN-817
tissue :
Myoblast .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-106; ASN-114; ASN-332; ASN-606; ASN-783; ASN-784; ASN-785 AND ASN-817